Projecte: SARS-CoV-2 specific T cell donor bank.
Responsabilitats i funcions principals
Estudiar la resposta immunològica cel·lular contra el SARS-CoV-2, mitjançant la caracterització de les cèl·lules T en donants immunitzats, així com desenvolupar línies de cèl·lules T específiques, per a crear un banc de limfòcits T específics contra SARS-CoV-2.
Requisits
Competències
Mèrits a valorar
Oferim
Oferim un lloc de treball amb les següents característiques:
Procés de selecció
Els candidats interessats hauran d'adjuntar a la següent adreça, una carta de presentació, un curriculum vitae complet i un mínim de 2 referències: frudilla@bst.cat
The Mouse Models of Cancer Therapies group from VHIO seeks a PhD student to join our group
Application deadline: 13/9/2020
Job description:
The Mouse Models of Cancer Therapies group led by ICREA Research Professor Laura Soucek is seeking an excellent and highly motivated PhD student to join us on a project supported by La Marató Foundation to study the role of Myc in instructing the tumor immune microenvironment in Non-Small-Cell Lung Cancer (NSCLC) with diverse mutational landscapes.
The group’s main interest is the role of Myc in tumorigenesis and Myc inhibition as a valuable approach in cancer therapy. Its main lines of research are (i) Myc-induced tumorigenesis, (ii) Myc inhibition and its validation as cancer therapy, (iii) design and testing of clinically-viable protein-based Myc inhibitors, (iv) development of pre-clinical models of cancer therapy and (v) Myc-induced cancer immune evasion.
The laboratory regularly works with several transgenic, syngeneic, humanized and patient-derived xenograft (PDX) mouse models of cancer, including lung, glioma, breast, colorectal, melanoma, Burkitt’s lymphoma and multiple myeloma models, with a very translational approach. The group overarching goal is to bring Myc inhibition to the clinic.
Requirements:
We are seeking enthusiastic, highly motivated and qualified PhD students. Candidates must have an exceptional academic record and hold a Master’s Degree to be eligible for highly competitive fellowships. A background in immunology /immune-oncology will be favorably considered.
Education and qualifications
• Degree in life sciences
• Master’s Degree in life sciences
Experience and knowledge
• Previous experience in at least one research laboratory
• Animal Experimentation Certificate is preferred
• Experience in cell culture, flow cytometry and mouse handling is preferred
• Excellent organization and communication skills
• Ability to work independently as well as part of a team
• High level of English
Main responsibilities and duties
• Planning and execution of research projects under supervision
• Use of immunology and cell culture techniques, as well as handling of different animal models
• Presentation of research results at internal and external meetings
Application:
To join our group and contribute to this exciting research project, applicants should send a CV, contact information of at least one reference and a cover letter describing past achievements and research interests to: Sílvia Casacuberta scasacuberta@vhio.net and Jonathan Whitfield jwhitfield@vhio.net